The CNI Administrative Office is a Columbia University research department in both the School of Arts & Sciences and the School of Engineering and Applied Science.

The Center presently supports multi-disciplinary research in the Departments of Applied Physics and Mathematics, Chemical Engineering, Chemistry, Electrical Engineering, Mechanical Engineering and Physics. The administrative staff supports principal investigators in all administrative aspects of grant management. The center serves as liaison to central university departments including the Office of Projects and Grants, Human Resources, the Controller's Office, Purchasing, Accounts Payable and Facilities.

Among the many streamlined processes the center has designed is a unique computerized accounting system. This system produces monthly reconciliations and performs multiple reporting functions. In addition, the center sponsors at least 15-20 seminars per semester which bring diverse experts nationwide to speak to the university community.